You Can Avoid Alzheimer’s Disease

by Janet Simpson Benvenuti

Getting Alzheimer’s disease is not inevitable with age. In a recent TED talk, Dr. Lisa Genova, neuroscientist, Massachusetts native and author of several books including Still Alice shared five ways you can avoid cognitive impairment.

You likely know the first four.

1. Get a good night’s sleep;
2. Follow the Mediterranean diet;
3. Exercise several times a week; aerobic exercise is best with strength training to enable fitness; and,
4. Lower your stress levels through prayer, yoga, or meditation.

What often surprises people is the fifth preventative: Learn something new. Exercising your brain through new experiences builds synaptic capacity. Lisa referred to the now famous Nun Study, research that followed the lives of 678 nuns who generously agreed to allow their brains to be autopsied upon their passing at ages 75 to 107. To their surprise, the researchers found that several nuns’ brains had the telltale Alzheimer’s lesions yet these women displayed no evidence of cognitive impairment while alive. Why? Their brains had ample capacity because of a lifetime of learning.

Watch the video. Share this post with your friends and family. Then join me in learning a new language using an app like Duolingo. Au revoir und auf wiedersehen.

c Circle of Life Partners, LLC. All rights reserved.

Of Mice and Women: His and Her Healthcare

Lab Miceby Janet Simpson Benvenuti

What do mice have to do with men and women’s health? It turns out, nearly everything.

Here are a few surprising facts.

  • Most medical research begins in laboratories using mice. Until 20 years ago, researchers used only male mice, finding the hormonal cycles of female mice an ‘unnecessary’ complication in experimental design.
  • Despite laws today that require all government-funded research to include females in animal and human studies, the sex of the animals is not often stated in published results.
  • Further, when clinical trials begin, researchers frequently do not enroll adequate numbers of women or, when they do, they fail to report data separately by sex.

Why does sex matter? Because many diseases, medications, and medical devices impact men and women differently. Here are just a few examples.

Perhaps you saw the report filed by Leslie Stahl on 60 Minutes about Ambien, a commonly prescribed medication, that found women need half the dosing typically recommended by their physicians. Do other drugs need to be adjusted? Most likely, we just don’t know which ones.

Perhaps you know that more women die each year from lung cancer than from breast, ovarian and uterine cancers combined, and that nonsmoking women are three times more likely than nonsmoking men to get lung cancer. We still don’t know why.

Perhaps you  watched Dr. Johnson’s TED talk, where she explained sex differences in heart disease and depression, cancer and Alzheimer’s disease and how attention to sex differences in medical research that is already funded and underway will benefit both men AND women’s health.

What does this mean for you and your family?

Make it a habit to ask your physicians if the treatment, diagnostic tests, or medications being prescribed work differently for women and men. They may not know the answer when you ask, but the question may prompt them to find out.

Read “Why Women’s Health Can’t Wait” written by the Connor’s Center for Women’s Health and Gender Biology. Join their Call to Action to hold federal agencies, medical device and pharmaceutical researchers accountable for how their studies address sex.

Consider supporting the work of Dr. Johnson and her colleagues, tireless advocates for Women’s Health, as they work with Congress and leading research institutions to address this issue.

Collectively, we can improve the health of our mothers and grandmothers, sisters and daughters as well as the men in our lives by insisting that the science behind health care accounts for sex differences.

Who knew that mice were so important to our health and well-being?

© 2014 Circle of Life Partners, LLC. All rights reserved.